| 产品名称 | Anti-T-bet antibody |
| 产品货号 | BO3061 |
| 交叉反应 | human, mouse, rat |
| 应用范围 | FC, WB, IHC, IF |
| 推荐稀释比 | FC 1:50 ,WB 1:1000-2000, IHC 1:50-300, IF 1:200 |
| 蛋白分子量 | 56-68KDa |
| 抗体来源 | Rabbit |
| 产品类型 | Polyclonal Antibody |
| 性状 | Liquid |
| 储存 | -20℃ |
| 背景资料 | T-box transcription factor TBX21 is a protein that in humans is encoded by the TBX21 gene. It is mapped to 17q21.32. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain,the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine,interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells,suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. |
